A firefighting helicopter was sent to the scene.
Fire crews battled a blaze at an auto body shop near Lindbergh Field on Tuesday morning.
Plumes of thick black smoke could be seen in surrounding neighborhoods near the 4000 block of Pacific Highway.
Firefighters say the blaze was reported at approximately 8:30 am at the Diko Auto Repair shop.
Multiple teams including an air unit were dispatched to the scene.
The owner told the local ABC affiliate that he has no idea how the fire started and saw the smoke as he made his way to work.
There have been no reports of injuries.